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產(chǎn)品規(guī)格
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BN41963R-50ul
50ul
￥1486.00
交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應用：WB,IHC-P,Flow-Cyt,ELISA
BN41963R-100ul
100ul
￥2360.00
交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應用：WB,IHC-P,Flow-Cyt,ELISA
BN41963R-200ul
200ul
￥3490.00
交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推薦應用：WB,IHC-P,Flow-Cyt,ELISA
產(chǎn)品描述
| 英文名稱 | GPR55 |
| 中文名稱 | 蛋白偶聯(lián)受體55抗體 |
| 別 名 | GPCR GPR55; G protein coupled receptor 55; G protein-coupled receptor 55; G protein-coupled receptor 55; GPCR GPR55; GPR 55; GPR55; Probable G protein coupled receptor 55; GPR55_HUMAN. |
| 研究領域 | 心血管 細胞生物 信號轉(zhuǎn)導 G蛋白偶聯(lián)受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, (predicted: Chicken, Dog, Horse, Rabbit, ) |
| 產(chǎn)品應用 | WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=2ug/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 37kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPR55:141-240/319 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR55 is a member of this family (subfamily Orphan-A). It has been reported to be expressed in the brain, where mRNA transcripts were detected in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain. ESTs have been isolated from liver/spleen libraries. Function: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. Expressed in osteoclasts and osteoblasts. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q9Y2T6 Gene ID: 9290 Database links: Entrez Gene: 9290 Human Omim: 604107 Human SwissProt: Q9Y2T6 Human Unigene: 114545 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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